Matthew Breuer
Graduate Student
Sachs Lab
Email: mbreuer@bio.tamu.edu
Education
- B.S. Biomedical Sciences, Minor in Philosophy, Sam Houston State University, 2016.
- M.S. Biology, Sam Houston State University. 2018.
- Ph.D. Biology, In Progress, Texas A&M University.
Awards
- Merit fellowship – College of Science TAMU
- Cell biology
- Flow cytometry
- Fluorescence microscopy
- Fungal biology
- Novel antimicrobial discovery
Publications:
- Sachs, H. Sampath, R. Marmorstein, and G. M. Carman. 2025. ‘The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases’, J Lipid Res, 66: 100711.
- Breuer, M.R. Dasgupta, A.D. Vasselli, J.G. Shaw, B.D. Sachs, M.S. The Antidepressant Sertraline Induces the Formation of Supersized Lipid Droplets in the Human Pathogen Cryptococcus neoformans. J Fungi (Basel). 2022 Jun 17;8(6):642. doi: 10.3390/jof8060642. PMID: 35736125; PMCID: PMC9224953
Presentations:
- Breuer, M.R. Beebe, K. McCann, O.G. Darji, D. Sangare, L.O. Sachs, M.S. 2023. Repurposing the antidepressant sertraline to combat microbial brain infections. Poster presentation given at the Texas A&M Land-Grant Meeting. Prairie View, Texas. April 2023.
- Breuer, M.R. Sachs, M.S. 2023. The antidepressant sertraline reduces the incorporation of an orthogonal amino acid into protein in the human pathogen Cryptococcus neoformans. Poster presentation given at the Texas A&M Life Sciences Symposium. College Station, Texas. February 2023.
- Breuer, M.R. Dasgupta, A.D. Vasselli, J.G. Shaw, B.D. Sachs, M.S. 2022. The Antidepressant Sertraline Induces the Formation of Supersized Lipid Droplets in the Human Pathogen Cryptococcus neoformans. Seminar given to the TAMU Biology Department. College Station, Texas. September 2022.
- Breuer, M.R. Dasgupta, A.D. Vasselli, J.G. Shaw, B.D. Sachs, M.S. 2022. The Antidepressant Sertraline Induces the Formation of Supersized Lipid Droplets in the Human Pathogen Cryptococcus neoformans. Oral presentation given at the South Central Medical Mycology conference. San Antonio, Texas. April 2022.
- Breuer, M.R. Dasgupta, A.D. Vasselli, J.G. Shaw, B.D. Sachs, M.S. 2022. Cellular Assessment of the Antifungal Effects of Sertraline in the Human Pathogen Cryptococcus neoformans. Poster presentation given at the Texas A&M Life Sciences Symposium. College Station, Texas. February 2022.
- Breuer, M.R. Dasgupta, A.D. Vasselli, J.G. Shaw, B.D. Sachs, M.S. 2021. Cellular Assessment of the Antifungal Effects of Sertraline in the Human Pathogen Cryptococcus neoformans. Poster presentation given at the Neurospora 2021 Conference. Navasota, Texas. October 2021.
- Breuer, M.R. Dasgupta, A.D. Vasselli, J.G. Shaw, B.D. Sachs, M.S. 2021. Cellular Assessment of the Antifungal Effects of Sertraline in the Human Pathogen Cryptococcus neoformans. Poster presentation given at the Texas A&M Student Post-Doc Research Conference. College Station, Texas. October 2021.
- Breuer, M.R. Dasgupta, A.D. Sachs, M.S. 2020. Flow Cytometric Approaches for Assessing the Antifungal Effects of Sertraline in the Human Pathogen Cryptococcus neoformans. Poster presentation given at the Texas A&M Student Post-Doc Research Conference. College Station, Texas.
- Breuer, M.R. Dasgupta, A.D. Sachs, M.S. 2019. Assessing the Antifungal Effects of Sertraline in the Human Pathogen Cryptococcus neoformans Using Flow Cytometry. Poster presentation given at the Texas A&M Student Post-Doc Research Conference. College Station, Texas.
- Breuer, M.R. Gaillard, A.R. 2018. Large-Scale Prediction of Programmed Cell Death Genes and Reverse Genetic Analysis of Mutant Strains in Chlamydomonas reinhardtii. Poster presentation given at the 18th International Conference on the Cell and Molecular Biology of Chlamydomonas. Washington, D.C., Virginia.