• Microbiology
• Microbial Genetics
• Molecular Tools
• Microscopy

Publications:

Huang X, Johnson AE, Brehm JN, Do TVT, Auchtung TA, McCullough HC, Lerma AI, Haidacher SJ, Hoch KM, Horvath TD, Sorg JA, Haag AM, Auchtung JM. Clostridioides difficilecolonization is not mediated by bile salts and utilizes Stickland fermentation of proline in an in vitro mSphere. 2025 Feb 25;10(2):e0104924. doi: 10.1128/msphere.01049-24. Epub 2025 Jan 16. PMID: 39817755; PMCID: PMC11852769.

Nerber HN, Baloh M, Brehm JN, Sorg JA. The small acid-soluble proteins of Clostridioides difficileregulate sporulation in a SpoIVB2-dependent manner. bioRxiv [Preprint]. 2024 Jun 25:2023.05.17.541253. doi: 10.1101/2023.05.17.541253. PMID: 37292792; PMCID: PMC10245694.

Osborne MS, Brehm JN, Olivença C, Cochran AM, Serrano M, Henriques AO, Sorg JA. The impact of YabG mutations on C. difficile spore germination and processing of spore substrates. bioRxiv [Preprint]. 2024 Jun 10:2024.06.10.598338. doi: 10.1101/2024.06.10.598338. PMID: 38915615; PMCID: PMC11195116.

Brehm JN, Sorg JA. Theophylline-based control of repA on a Clostridioides difficile plasmid for use in allelic exchange. Anaerobe. 2024 Apr 29;88:102858. doi: 10.1016/j.anaerobe.2024.102858. Epub ahead of print. PMID: 38692475.

Presentations:

2025 Annual Student Postdoctoral Research Conference, Department of Biology, Texas A&M University – Poster

2024 Annual Student Postdoctoral Research Conference, Department of Biology, Texas A&M University – Poster