• Cancer Bioinformatics
• Cancer Metabolomics
• Nanotechnology
• Mechanobiology

An aberrant activation of the biological process, termed epithelial-mesenchymal transition (EMT) plays an important role for the acquisition of malignant phenotypes as well as cancer stem cells (CSC) properties by epithelial cancer cells. EMT facilitates the metastatic dissemination which is the major cause of cancer related mortality. The main focus of my work is to identify the molecular mechanisms that induces EMT, and to develop novel therapeutic strategies for preventing and treating metastasis.

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2. Giri, B, Roy Sarkar, T. Editorial: The role of cancer associated fibroblast (CAF) in EMT/metastasis in malignancies of epithelial tissues. Front Cell Dev Biol. 2024;12 :1384150. doi: 10.3389/fcell.2024.1384150. PubMed PMID:38481527 PubMed Central PMC10933097.
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6. Maity, AK, Lee, SC, Hu, L, Bell-Pedersen, D, Mallick, BK, Sarkar, TR et al.. Circadian Gene Selection for Time-to-event Phenotype by Integrating CNV and RNAseq Data. Chemometr Intell Lab Syst. 2021;212 :. doi: 10.1016/j.chemolab.2021.104276. PubMed PMID:35068632 PubMed Central PMC8775911.
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9. Maity, AK, Lee, SC, Mallick, BK, Sarkar, TR. Bayesian structural equation modeling in multiple omics data with application to circadian genes. Bioinformatics. 2020;36 (13):3951-3958. doi: 10.1093/bioinformatics/btaa286. PubMed PMID:32369552 PubMed Central PMC7332567.
10. Roy Sarkar, T, Maity, AK, Niu, Y, Mallick, BK. Multiple Omics Data Integration to Identify Long Noncoding RNA Responsible for Breast Cancer-Related Mortality. Cancer Inform. 2019;18 :1176935119871933. doi: 10.1177/1176935119871933. PubMed PMID:31488946 PubMed Central PMC6710679.
11. Sarkar T.R., Niu, Y, Mallick, B.K., Wu, G. Intakes of amino acids and other nutrients by adult humans. Adv Exp Med Biol. 2021, 1332:211-227.
12. Maity, AK., Lee, S-C., Hu, L., Bell-Pedersen., D., Mallick, BK, Sarkar T. R. Significant Circadian Gene Selection for Time-to-event Phenotype by Integrating CNV and RNAseq Data. Chemometrics and Intelligent Laboratory Systems, 2021, 212, 104276.